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Smoothing Protein Energy Landscapes by Integrating Folding Models with Structure Prediction
Decades of work has investigated the energy landscapes of simple protein models, but what do the landscapes of real, large, atomically detailed proteins look like? We explore an approach to this problem that systematically extracts simple funnel models of actual proteins using ensembles of structure...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207166/ https://ncbi.nlm.nih.gov/pubmed/22067165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.036 |
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