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Smoothing Protein Energy Landscapes by Integrating Folding Models with Structure Prediction

Decades of work has investigated the energy landscapes of simple protein models, but what do the landscapes of real, large, atomically detailed proteins look like? We explore an approach to this problem that systematically extracts simple funnel models of actual proteins using ensembles of structure...

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Autors principals: Pritchard-Bell, Ari, Shell, M. Scott
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207166/
https://ncbi.nlm.nih.gov/pubmed/22067165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.036
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