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Crowding of Molecular Motors Determines Microtubule Depolymerization
The assembly and disassembly dynamics of microtubules (MTs) is tightly controlled by MT-associated proteins. Here, we investigate how plus-end-directed depolymerases of the kinesin-8 family regulate MT depolymerization dynamics. Using an individual-based model, we reproduce experimental findings. Mo...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207156/ https://ncbi.nlm.nih.gov/pubmed/22067158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.009 |
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