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Molecular crowding creates traffic jams of kinesin motors on microtubules

Despite the crowdedness of the interior of cells, microtubule-based motor proteins are able to deliver cargoes rapidly and reliably throughout the cytoplasm. We hypothesize that motor proteins may be adapted to operate in crowded environments by having molecular properties that prevent them from for...

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Autori principali: Leduc, Cécile, Padberg-Gehle, Kathrin, Varga, Vladimír, Helbing, Dirk, Diez, Stefan, Howard, Jonathon
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341076/
https://ncbi.nlm.nih.gov/pubmed/22431622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107281109
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