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Molecular crowding creates traffic jams of kinesin motors on microtubules

Despite the crowdedness of the interior of cells, microtubule-based motor proteins are able to deliver cargoes rapidly and reliably throughout the cytoplasm. We hypothesize that motor proteins may be adapted to operate in crowded environments by having molecular properties that prevent them from for...

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Bibliografische gegevens
Hoofdauteurs: Leduc, Cécile, Padberg-Gehle, Kathrin, Varga, Vladimír, Helbing, Dirk, Diez, Stefan, Howard, Jonathon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3341076/
https://ncbi.nlm.nih.gov/pubmed/22431622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107281109
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