Crowding of Molecular Motors Determines Microtubule Depolymerization

The assembly and disassembly dynamics of microtubules (MTs) is tightly controlled by MT-associated proteins. Here, we investigate how plus-end-directed depolymerases of the kinesin-8 family regulate MT depolymerization dynamics. Using an individual-based model, we reproduce experimental findings. Mo...

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Bibliographic Details
Main Authors: Reese, Louis, Melbinger, Anna, Frey, Erwin
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2011
Subjects:
Muscle, Motility, and Motor Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207156/
https://ncbi.nlm.nih.gov/pubmed/22067158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.009
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