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Rapid Synthesis of the X-linked Mental Retardation Protein OPHN1 Mediates mGluR-Dependent LTD through Interaction with the Endocytic Machinery

Activation of group I metabotropic glutamate receptors leads to long-term depression (mGluR-LTD). Alterations in this form of plasticity have been linked to drug addiction and cognitive disorders. A key characteristic of mGluR-LTD is its dependence on rapid protein synthesis; however, the identities...

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Detalhes bibliográficos
Main Authors: Nadif Kasri, Nael, Nakano-Kobayashi, Akiko, Van Aelst, Linda
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206629/
https://ncbi.nlm.nih.gov/pubmed/22017989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.09.001
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