Enhanced Synaptic Activity and Epileptiform Events in the Embryonic KCC2 Deficient Hippocampus

The neuronal potassium-chloride co-transporter 2 [indicated thereafter as KCC2 (for protein) and Kcc2 (for gene)] is thought to play an important role in the post natal excitatory to inhibitory switch of GABA actions in the rodent hippocampus. Here, by studying hippocampi of wild-type (Kcc2(+/+)) an...

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Autors principals: Khalilov, Ilgam, Chazal, Geneviève, Chudotvorova, Ilona, Pellegrino, Christophe, Corby, Séverine, Ferrand, Nadine, Gubkina, Olena, Nardou, Romain, Tyzio, Roman, Yamamoto, Sumii, Jentsch, Thomas J., Hübner, Christian A., Gaiarsa, Jean-Luc, Ben-Ari, Yehezkel, Medina, Igor
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2011
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206525/
https://ncbi.nlm.nih.gov/pubmed/22065950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2011.00023
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