Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival

ABSTRACT: KCC2 is a neuron-specific potassium–chloride co-transporter controlling intracellular chloride homeostasis in mature and developing neurons. It is implicated in the regulation of neuronal migration, dendrites outgrowth and formation of the excitatory and inhibitory synaptic connections. Th...

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Detalhes bibliográficos
Main Authors: Pellegrino, Christophe, Gubkina, Olena, Schaefer, Michael, Becq, Hélène, Ludwig, Anastasia, Mukhtarov, Marat, Chudotvorova, Ilona, Corby, Severine, Salyha, Yuriy, Salozhin, Sergey, Bregestovski, Piotr, Medina, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115820/
https://ncbi.nlm.nih.gov/pubmed/21486764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.203703
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