Early expression of KCC2 in rat hippocampal cultures augments expression of functional GABA synapses

The development of GABAergic synapses is associated with an excitatory to inhibitory shift of the actions of GABA because of a reduction of [Cl(−)](i). This is due to a delayed postnatal expression of the K(+)–Cl(−) cotransporter KCC2, which has low levels at birth and peaks during the first few pos...

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Bibliographic Details
Main Authors: Chudotvorova, Ilona, Ivanov, Anton, Rama, Sylvain, Hübner, Christian A, Pellegrino, Christophe, Ben-Ari, Yehezkel, Medina, Igor
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2005
Subjects:
Cell Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464776/
https://ncbi.nlm.nih.gov/pubmed/15961425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.089821
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