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Early expression of KCC2 in rat hippocampal cultures augments expression of functional GABA synapses
The development of GABAergic synapses is associated with an excitatory to inhibitory shift of the actions of GABA because of a reduction of [Cl(−)](i). This is due to a delayed postnatal expression of the K(+)–Cl(−) cotransporter KCC2, which has low levels at birth and peaks during the first few pos...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464776/ https://ncbi.nlm.nih.gov/pubmed/15961425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.089821 |
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