Early expression of KCC2 in rat hippocampal cultures augments expression of functional GABA synapses

The development of GABAergic synapses is associated with an excitatory to inhibitory shift of the actions of GABA because of a reduction of [Cl(−)](i). This is due to a delayed postnatal expression of the K(+)–Cl(−) cotransporter KCC2, which has low levels at birth and peaks during the first few pos...

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Main Authors: Chudotvorova, Ilona, Ivanov, Anton, Rama, Sylvain, Hübner, Christian A, Pellegrino, Christophe, Ben-Ari, Yehezkel, Medina, Igor
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2005
主題:
Cell Physiology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464776/
https://ncbi.nlm.nih.gov/pubmed/15961425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.089821
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