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Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection

We and others have reported that simultaneous targeted deletion of CB(1) and CB(2) resulted in exacerbation of immune reactivity, suggesting a role of endocannabinoids in down-regulating immune function. In this study, we demonstrate that APC function is enhanced specifically in the absence of CB(1)...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Karmaus, Peer W. F., Chen, Weimin, Crawford, Robert B., Harkema, Jack R., Kaplan, Barbara L. F., Kaminski, Norbert E.
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Leukocyte Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206470/
https://ncbi.nlm.nih.gov/pubmed/21873455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0511219
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