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Δ(9)-Tetrahydrocannabinol Suppresses Cytotoxic T Lymphocyte Function Independent of CB(1) and CB(2), Disrupting Early Activation Events
Previously, CD8(+) T cells were found to be a sensitive target for suppression by Δ(9)-tetrahydrocannabinol (Δ(9)-THC) in a murine model of influenza infection. To study the effect of Δ(9)-THC on CD8(+) cytotoxic T lymphocytes (CTL), an allogeneic model of MHC I mismatch was used to elicit CTL. In a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266990/ https://ncbi.nlm.nih.gov/pubmed/21789506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-011-9293-4 |
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