Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial

BACKGROUND: In cardiopulmonary bypass (CPB) patients, fibrinolysis may enhance postoperative inflammatory response. We aimed to determine whether an additional postoperative dose of antifibrinolytic tranexamic acid (TA) reduced CPB-mediated inflammatory response (IR). METHODS: We performed a randomi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jiménez, Juan J, Iribarren, José L, Brouard, Maitane, Hernández, Domingo, Palmero, Salomé, Jiménez, Alejandro, Lorente, Leonardo, Machado, Patricia, Borreguero, Juan M, Raya, José M, Martín, Beatriz, Pérez, Rosalía, Martínez, Rafael, Mora, María L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206427/
https://ncbi.nlm.nih.gov/pubmed/21999189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-6-138
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