Tranexamic acid attenuates inflammatory response in cardiopulmonary bypass surgery through blockade of fibrinolysis: a case control study followed by a randomized double-blind controlled trial

INTRODUCTION: Extracorporeal circulation induces hemostatic alterations that lead to inflammatory response (IR) and postoperative bleeding. Tranexamic acid (TA) reduces fibrinolysis and blood loss after cardiopulmonary bypass (CPB). However, its effects on IR and vasoplegic shock (VS) are not well k...

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Main Authors: Jimenez, Juan J, Iribarren, Jose L, Lorente, Leonardo, Rodriguez, Jose M, Hernandez, Domingo, Nassar, Ibrahim, Perez, Rosalia, Brouard, Maitane, Milena, Antonio, Martinez, Rafael, Mora, Maria L
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246206/
https://ncbi.nlm.nih.gov/pubmed/17988379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6173
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