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Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial

BACKGROUND: In cardiopulmonary bypass (CPB) patients, fibrinolysis may enhance postoperative inflammatory response. We aimed to determine whether an additional postoperative dose of antifibrinolytic tranexamic acid (TA) reduced CPB-mediated inflammatory response (IR). METHODS: We performed a randomi...

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Bibliografiske detaljer
Main Authors: Jiménez, Juan J, Iribarren, José L, Brouard, Maitane, Hernández, Domingo, Palmero, Salomé, Jiménez, Alejandro, Lorente, Leonardo, Machado, Patricia, Borreguero, Juan M, Raya, José M, Martín, Beatriz, Pérez, Rosalía, Martínez, Rafael, Mora, María L
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206427/
https://ncbi.nlm.nih.gov/pubmed/21999189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-6-138
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