Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial

BACKGROUND: In cardiopulmonary bypass (CPB) patients, fibrinolysis may enhance postoperative inflammatory response. We aimed to determine whether an additional postoperative dose of antifibrinolytic tranexamic acid (TA) reduced CPB-mediated inflammatory response (IR). METHODS: We performed a randomi...

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Autores principales: Jiménez, Juan J, Iribarren, José L, Brouard, Maitane, Hernández, Domingo, Palmero, Salomé, Jiménez, Alejandro, Lorente, Leonardo, Machado, Patricia, Borreguero, Juan M, Raya, José M, Martín, Beatriz, Pérez, Rosalía, Martínez, Rafael, Mora, María L
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206427/
https://ncbi.nlm.nih.gov/pubmed/21999189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-6-138
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