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Thiourea-Catalyzed Enantioselective Iso-Pictet–Spengler Reactions
[Image: see text] A one-pot condensation of isotryptamines and aldehydes that affords enantiomerically enriched 4-substituted tetrahydro-γ-carbolines is reported. The reaction is induced by a chiral thiourea/benzoic acid dual catalyst system. Purification of the N-Boc-protected products by triturati...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3206290/ https://ncbi.nlm.nih.gov/pubmed/21919478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol202300t |
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