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HtrA1 sensitizes ovarian cancer cells to cisplatin-induced cytotoxicity by targeting XIAP for degradation

HtrA1, a member of serine protease family, has been previously found to be involved in resistance to chemotherapy in ovarian cancer although the underlying mechanism is not clear. Using mixture-based oriented peptide library approach, we previously identified X-linked inhibitor of apoptosis protein...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: He, Xiaoping, Khurana, Ashwani, Maguire, Jacie L, Chien, Jeremy, Shridhar, Viji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206182/
https://ncbi.nlm.nih.gov/pubmed/21387310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26044
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