Enhancing the Identification of Phosphopeptides from Putative Basophilic Kinase Substrates Using Ti (IV) Based IMAC Enrichment

Metal and metal oxide chelating-based phosphopeptide enrichment technologies provide powerful tools for the in-depth profiling of phosphoproteomes. One weakness inherent to current enrichment strategies is poor binding of phosphopeptides containing multiple basic residues. The problem is exacerbated...

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Bibliografiske detaljer
Main Authors: Zhou, Houjiang, Low, Teck Y., Hennrich, Marco L., van der Toorn, Henk, Schwend, Thomas, Zou, Hanfa, Mohammed, Shabaz, Heck, Albert J. R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2011
Fag:
Technological Innovations and Resources
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205857/
https://ncbi.nlm.nih.gov/pubmed/21715320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.006452
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