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Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes

The degeneracy of the genetic code allows protein-coding DNA and RNA sequences to simultaneously encode additional, overlapping functional elements. A sequence in which both protein-coding and additional overlapping functions have evolved under purifying selection should show increased evolutionary...

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Detalhes bibliográficos
Main Authors: Lin, Michael F., Kheradpour, Pouya, Washietl, Stefan, Parker, Brian J., Pedersen, Jakob S., Kellis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205576/
https://ncbi.nlm.nih.gov/pubmed/21994248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.108753.110
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