METABOLICALLY STABILIZED DERIVATIVES OF PHOSPHATIDYLINOSITOL 4-PHOSPHATE: SYNTHESIS AND APPLICATIONS

Phosphatidylinositol-4-phosphate (PtdIns(4)P) is an essential component of eukaryotic membranes and a marker of the Golgi complex. The pivotal role of PtdIns(4)P in signaling and trafficking necessitates the development of synthetic derivatives of this lipid that are resistant to hydrolysis and ther...

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Detalhes bibliográficos
Main Authors: He, Ju, Gajewiak, Joanna, Scott, Jordan L., Gong, Denghuang, Ali, Muzaffar, Best, Michael D., Prestwich, Glenn D., Stahelin, Robert V., Kutateladze, Tatiana G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205354/
https://ncbi.nlm.nih.gov/pubmed/22035800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.07.022
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