Stabilized Phosphatidylinositol-5-Phosphate Analogues as Ligands for the Nuclear Protein ING2: Chemistry, Biology and Molecular Modeling

The interaction of PtdIns(5)P with the tumor suppressor protein ING2 has been implicated in the regulation of chromatin modification. To enhance the stability of PtdIns(5)P for studies of the biological role of in vivo, two phosphatase-resistant moieties were used to replace the labile 5-phosphate....

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Hlavní autoři: Huang, Wei, Zhang, Honglu, Davrazou, Foteini, Kutateladze, Tatiana G., Shi, Xiaobing, Gozani, Or, Prestwich, Glenn D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553394/
https://ncbi.nlm.nih.gov/pubmed/17469822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja070195b
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