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Stabilized Phosphatidylinositol-5-Phosphate Analogues as Ligands for the Nuclear Protein ING2: Chemistry, Biology and Molecular Modeling

The interaction of PtdIns(5)P with the tumor suppressor protein ING2 has been implicated in the regulation of chromatin modification. To enhance the stability of PtdIns(5)P for studies of the biological role of in vivo, two phosphatase-resistant moieties were used to replace the labile 5-phosphate....

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Huang, Wei, Zhang, Honglu, Davrazou, Foteini, Kutateladze, Tatiana G., Shi, Xiaobing, Gozani, Or, Prestwich, Glenn D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553394/
https://ncbi.nlm.nih.gov/pubmed/17469822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja070195b
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