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The p53-p21(WAF1) checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function

We previously identified FOXF1 as a potential tumor suppressor gene with an essential role in preventing DNA rereplication to maintain genomic stability, which is frequently inactivated in breast cancer through the epigenetic mechanism. Here we further addressed the role of the p53-p21(WAF1) checkpo...

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Detalhes bibliográficos
Main Authors: Lo, Pang-Kuo, Lee, Ji Shin, Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205208/
https://ncbi.nlm.nih.gov/pubmed/21964066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.09.017
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