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The p53-p21(WAF1) checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function
We previously identified FOXF1 as a potential tumor suppressor gene with an essential role in preventing DNA rereplication to maintain genomic stability, which is frequently inactivated in breast cancer through the epigenetic mechanism. Here we further addressed the role of the p53-p21(WAF1) checkpo...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205208/ https://ncbi.nlm.nih.gov/pubmed/21964066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.09.017 |
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