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Gas-phase purification enables accurate, large-scale, multiplexed proteome quantification with isobaric tagging
We describe a mass spectrometry method, QuantMode, which improves the accuracy of isobaric tag–based quantification by alleviating the pervasive problem of precursor interference—co-isolation of impurities—through gas-phase purification. QuantMode analysis of a yeast sample ‘contaminated’ with inter...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205195/ https://ncbi.nlm.nih.gov/pubmed/21963608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1716 |
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