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Analysis of tandem mass spectra by FTMS for improved large-scale proteomics with superior protein quantification

Using a newly developed dual-cell quadrupole linear ion trap-orbitrap hybrid mass spectrometer (dcQLT-orbitrap), we demonstrate the utility of collecting high-resolution tandem mass spectral data for large-scale shotgun proteomics. Multiple nanoLC-MS/MS experiments on both an older generation quadru...

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Bibliografiske detaljer
Main Authors: McAlister, Graeme C., Phanstiel, Doug, Wenger, Craig D., Lee, M. Violet, Coon, Joshua J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800853/
https://ncbi.nlm.nih.gov/pubmed/19938823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac902005s
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