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Automated gas-phase purification for accurate, multiplexed quantification on a stand-alone ion trap mass spectrometer

Isobaric tagging enables the acquisition of highly-multiplexed proteome quantification but is hindered by the pervasive problem of precursor interference. The elimination of co-isolated contaminants prior to reporter tag generation can be achieved through the use of gas-phase purification via proton...

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Autors principals: Vincent, Catherine E., Rensvold, Jarred W., Westphall, Michael S., Pagliarini, David J., Coon, Joshua J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568235/
https://ncbi.nlm.nih.gov/pubmed/23046161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac302156t
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