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Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions

OBJECTIVES: Cholesterol-rich nanoemulsions (LDE) bind to low-density lipoprotein (LDL) receptors and after injection into the bloodstream concentrate in aortas of atherosclerotic rabbits. Association of paclitaxel with LDE markedly reduces the lesions. In previous studies, treatment of refractory ca...

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Autors principals: Tavares, Elaine R, Freitas, Fatima R, Diament, Jayme, Maranhão, Raul C
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205126/
https://ncbi.nlm.nih.gov/pubmed/22072867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S24048
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