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Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions

OBJECTIVES: Cholesterol-rich nanoemulsions (LDE) bind to low-density lipoprotein (LDL) receptors and after injection into the bloodstream concentrate in aortas of atherosclerotic rabbits. Association of paclitaxel with LDE markedly reduces the lesions. In previous studies, treatment of refractory ca...

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Bibliografische gegevens
Hoofdauteurs: Tavares, Elaine R, Freitas, Fatima R, Diament, Jayme, Maranhão, Raul C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205126/
https://ncbi.nlm.nih.gov/pubmed/22072867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S24048
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