Reduction of atherosclerotic lesions in rabbits treated with etoposide associated with cholesterol-rich nanoemulsions

OBJECTIVES: Cholesterol-rich nanoemulsions (LDE) bind to low-density lipoprotein (LDL) receptors and after injection into the bloodstream concentrate in aortas of atherosclerotic rabbits. Association of paclitaxel with LDE markedly reduces the lesions. In previous studies, treatment of refractory ca...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tavares, Elaine R, Freitas, Fatima R, Diament, Jayme, Maranhão, Raul C
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2011
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205126/
https://ncbi.nlm.nih.gov/pubmed/22072867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S24048
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