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piRNA production requires heterochromatin formation in Drosophila
Protecting the genome from transposable element (TE) mobilization is critical for germline development. In Drosophila, Piwi proteins and their bound small RNAs (piRNAs) provide a potent defense against TE activity. TE targeting piRNAs are processed from TE-dense heterochromatic loci termed ‘piRNA cl...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205116/ https://ncbi.nlm.nih.gov/pubmed/21820311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.06.057 |
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