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An Epigenetic Role for Maternally Inherited piRNAs in Transposon Silencing

In plants and mammals, small RNAs indirectly mediate epigenetic inheritance by specifying cytosine methylation. We found that small RNAs themselves serve as vectors for epigenetic information. Crosses between Drosophila strains that differ in the presence of a particular transposon can produce steri...

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Bibliographic Details
Main Authors: Brennecke, Julius, Malone, Colin D., Aravin, Alexei A., Sachidanandam, Ravi, Stark, Alexander, Hannon, Gregory J.
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805124/
https://ncbi.nlm.nih.gov/pubmed/19039138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1165171
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