MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice

Mutations in human FYVE, RhoGEF, and PH domain–containing 1 (FGD1) cause faciogenital dysplasia (FGDY; also known as Aarskog syndrome), an X-linked disorder that affects multiple skeletal structures. FGD1 encodes a guanine nucleotide exchange factor (GEF) that specifically activates the Rho GTPase C...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zou, Weiguo, Greenblatt, Matthew B., Shim, Jae-Hyuck, Kant, Shashi, Zhai, Bo, Lotinun, Sutada, Brady, Nicholas, Hu, Dorothy Zhang, Gygi, Steven P., Baron, Roland, Davis, Roger J., Jones, Dallas, Glimcher, Laurie H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204846/
https://ncbi.nlm.nih.gov/pubmed/21965325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59041
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker