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Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype
Biliary atresia (BA) is a destructive cholangiopathy of childhood in which Th1 immunity has been mechanistically linked to the bile duct inflammation and obstruction that culminate in liver injury. Based on reports of decreased Th1 cytokines in some patients and the development of BA in mice lacking...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204839/ https://ncbi.nlm.nih.gov/pubmed/22005305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57728 |
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