Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotype

Biliary atresia (BA) is a destructive cholangiopathy of childhood in which Th1 immunity has been mechanistically linked to the bile duct inflammation and obstruction that culminate in liver injury. Based on reports of decreased Th1 cytokines in some patients and the development of BA in mice lacking...

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Bibliographic Details
Main Authors: Li, Jun, Bessho, Kazuhiko, Shivakumar, Pranavkumar, Mourya, Reena, Mohanty, Sujit Kumar, dos Santos, Jorge L., Miura, Irene K., Porta, Gilda, Bezerra, Jorge A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204839/
https://ncbi.nlm.nih.gov/pubmed/22005305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57728
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