Assessment of proteolytic degradation of the basement membrane: a fragment of type IV collagen as a biochemical marker for liver fibrosis

BACKGROUND: Collagen deposition and an altered matrix metalloproteinase (MMP) expression profile are hallmarks of fibrosis. Type IV collagen is the most abundant structural basement membrane component of tissue, which increases 14-fold during fibrogenesis in the liver. Proteolytic degradation of col...

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Hauptverfasser: Veidal, Sanne S, Karsdal, Morten A, Nawrocki, Arkadiusz, Larsen, Martin R, Dai, Yueqin, Zheng, Qinlong, Hägglund, Per, Vainer, Ben, Skjøt-Arkil, Helene, Leeming, Diana J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204229/
https://ncbi.nlm.nih.gov/pubmed/21970406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-4-22
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