Apolipoprotein E and LRP1 Increase Early in Parkinson's Disease Pathogenesis

Parkinson's disease (PD) is characterized by α-synuclein–containing Lewy bodies (LBs) and loss of melanized neurons in the substantia nigra (SN). Recently, a link between apolipoprotein E (ApoE) expression, α-synuclein aggregation, and neurodegeneration was suggested. Here, we report on ApoE ex...

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Autors principals: Wilhelmus, Micha M.M., Bol, John G.J.M., Van Haastert, Elise S., Rozemuller, Annemieke J.M., Bu, Guojun, Drukarch, Benjamin, Hoozemans, Jeroen J.M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204035/
https://ncbi.nlm.nih.gov/pubmed/21907175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.021
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