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The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer’s Disease Hippocampus
Accumulation of misfolded proteins in the endoplasmic reticulum triggers a cellular stress response called the unfolded protein response (UPR) that protects the cell against the toxic buildup of misfolded proteins. Previously, we reported that UPR activation is increased in Alzheimer’s disease (AD)...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Investigative Pathology
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671357/ https://ncbi.nlm.nih.gov/pubmed/19264902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080814 |
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