The Unfolded Protein Response Is Activated in Pretangle Neurons in Alzheimer’s Disease Hippocampus

Accumulation of misfolded proteins in the endoplasmic reticulum triggers a cellular stress response called the unfolded protein response (UPR) that protects the cell against the toxic buildup of misfolded proteins. Previously, we reported that UPR activation is increased in Alzheimer’s disease (AD)...

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Main Authors: Hoozemans, Jeroen J.M., van Haastert, Elise S., Nijholt, Diana A.T., Rozemuller, Annemieke J.M., Eikelenboom, Piet, Scheper, Wiep
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671357/
https://ncbi.nlm.nih.gov/pubmed/19264902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080814
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