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Acid Sphingomyelinase Gene Deficiency Ameliorates the Hyperhomocysteinemia-Induced Glomerular Injury in Mice

Hyperhomocysteinemia (hHcys) enhances ceramide production, leading to the activation of NADPH oxidase and consequent glomerular oxidative stress and sclerosis. The present study was performed to determine whether acid sphingomyelinase (Asm), a ceramide-producing enzyme, is implicated in the developm...

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Detaylı Bibliyografya
Asıl Yazarlar: Boini, Krishna M., Xia, Min, Li, Caixia, Zhang, Chun, Payne, Lori P., Abais, Justine M., Poklis, Justin L., Hylemon, Philip B., Li, Pin-Lan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204029/
https://ncbi.nlm.nih.gov/pubmed/21893018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.019
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