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Inflammation-Induced Endothelial-to-Mesenchymal Transition: A Novel Mechanism of Intestinal Fibrosis

In addition to mesenchymal cells, endothelial cells may contribute to fibrosis through the process of endothelial-to-mesenchymal transition (EndoMT). We investigated whether human intestinal microvascular endothelial cells (HIMEC) undergo EndoMT and contribute to fibrosis in human and experimental i...

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Autori principali: Rieder, Florian, Kessler, Sean P., West, Gail A., Bhilocha, Shardul, de la Motte, Carol, Sadler, Tammy M., Gopalan, Banu, Stylianou, Eleni, Fiocchi, Claudio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204019/
https://ncbi.nlm.nih.gov/pubmed/21945322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.042
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