The Epithelial Danger Signal IL-1α Is a Potent Activator of Fibroblasts and Reactivator of Intestinal Inflammation

Intestinal epithelial cell (IEC) death is typical of inflammatory bowel disease (IBD). We investigated: i) whether IEC–released necrotic cell products (proinflammatory mediators) amplify mucosal inflammation, ii) the capacity of necrotic cell lysates from HT29 cells or human IECs to induce human int...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Am J Pathol
Autores principales: Scarpa, Melania, Kessler, Sean, Sadler, Tammy, West, Gail, Homer, Craig, McDonald, Christine, de la Motte, Carol, Fiocchi, Claudio, Stylianou, Eleni
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2015
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450321/
https://ncbi.nlm.nih.gov/pubmed/25864926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.02.018
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares