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Astrocytes carrying the superoxide dismutase 1 (SOD1(G93A)) mutation induce wild-type motor neuron degeneration in vivo
Recent studies highlight astrocytes as key drivers of motor neuron (MN) degeneration and disease propagation in mutant human superoxide dismutase 1 (mSOD1)-mediated amyotrophic lateral sclerosis. However, in vivo analysis of specific astrocytic influence in amyotrophic lateral sclerosis has proven d...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203804/ https://ncbi.nlm.nih.gov/pubmed/21969586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103141108 |
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