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Astrocytes carrying the superoxide dismutase 1 (SOD1(G93A)) mutation induce wild-type motor neuron degeneration in vivo

Recent studies highlight astrocytes as key drivers of motor neuron (MN) degeneration and disease propagation in mutant human superoxide dismutase 1 (mSOD1)-mediated amyotrophic lateral sclerosis. However, in vivo analysis of specific astrocytic influence in amyotrophic lateral sclerosis has proven d...

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Detalhes bibliográficos
Main Authors: Papadeas, Sophia T., Kraig, Sarah E., O'Banion, Colin, Lepore, Angelo C., Maragakis, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203804/
https://ncbi.nlm.nih.gov/pubmed/21969586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1103141108
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