Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand

We describe a crystal structure, at atomic resolution (1.1 Å, 100 K), of a ruthenium polypyridyl complex bound to duplex DNA, in which one ligand acts as a wedge in the minor groove, resulting in the 51° kinking of the double helix. The complex cation Λ-[Ru(1,4,5,8-tetraazaphenanthrene)(2)(dipyridop...

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Detalhes bibliográficos
Main Authors: Hall, James P., O’Sullivan, Kyra, Naseer, Abeer, Smith, Jayden A., Kelly, John M., Cardin, Christine J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203786/
https://ncbi.nlm.nih.gov/pubmed/21969542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108685108
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