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Flexibility of short ds-DNA intercalated by a dipyridophenazine ligand

We use Förster Resonant Energy Transfer (FRET) in order to measure the increase of flexibility of short ds-DNA induced by the intercalation of dipyridophenazine (dppz) ligand in between DNA base pairs. By using a DNA double strand fluorescently labeled at its extremities, it is shown that the end-to...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Jia, Fuchao, Despax, Stéphane, Münch, Jean-Pierre, Hébraud, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399336/
https://ncbi.nlm.nih.gov/pubmed/25932461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2015.00025
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