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Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids
The mechanisms permitting nonpolymorphic CD1 molecules to present lipid antigens that differ considerably in polar head and aliphatic tails remain elusive. It is also unclear why hydrophobic motifs in the aliphatic tails of some antigens, which presumably embed inside CD1 pockets, contribute to dete...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203780/ https://ncbi.nlm.nih.gov/pubmed/22006319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110118108 |
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