Structural reorganization of the antigen-binding groove of human CD1b for presentation of mycobacterial sulfoglycolipids

The mechanisms permitting nonpolymorphic CD1 molecules to present lipid antigens that differ considerably in polar head and aliphatic tails remain elusive. It is also unclear why hydrophobic motifs in the aliphatic tails of some antigens, which presumably embed inside CD1 pockets, contribute to dete...

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Bibliographic Details
Main Authors: Garcia-Alles, Luis F., Collmann, Anthony, Versluis, Cees, Lindner, Buko, Guiard, Julie, Maveyraud, Laurent, Huc, Emilie, Im, Jin S., Sansano, Sebastiano, Brando, Thérèse, Julien, Sylviane, Prandi, Jacques, Gilleron, Martine, Porcelli, Steven A., de la Salle, Henri, Heck, Albert J. R., Mori, Lucia, Puzo, Germain, Mourey, Lionel, De Libero, Gennaro
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203780/
https://ncbi.nlm.nih.gov/pubmed/22006319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110118108
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