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Reprogramming of ovine adult fibroblasts to pluripotency via drug-inducible expression of defined factors

Reprogramming of somatic cells in the enucleated egg made Dolly, the sheep, the first successfully cloned mammal in 1996. However, the mechanism of sheep somatic cell reprogramming has not yet been addressed. Moreover, sheep embryonic stem (ES) cells are still not available, which limits the generat...

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Detalhes bibliográficos
Main Authors: Bao, Lei, He, Lixiazi, Chen, Jijun, Wu, Zhao, Liao, Jing, Rao, Lingjun, Ren, Jiangtao, Li, Hui, Zhu, Hui, Qian, Lei, Gu, Yijun, Dai, Huimin, Xu, Xun, Zhou, Jinqiu, Wang, Wen, Cui, Chun, Xiao, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203662/
https://ncbi.nlm.nih.gov/pubmed/21221129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.6
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