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Reprogramming of ovine adult fibroblasts to pluripotency via drug-inducible expression of defined factors
Reprogramming of somatic cells in the enucleated egg made Dolly, the sheep, the first successfully cloned mammal in 1996. However, the mechanism of sheep somatic cell reprogramming has not yet been addressed. Moreover, sheep embryonic stem (ES) cells are still not available, which limits the generat...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203662/ https://ncbi.nlm.nih.gov/pubmed/21221129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.6 |
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