Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1

Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by the transcription factors Oct4, Sox2, and Klf4 in combination with c-Myc. Recently, Sox2 plus Oct4 was shown to reprogram fibroblasts and Oct4 alone was able to reprogram mouse and human neural stem cells (NSCs) into iPS...

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Autori principali: Moon, Jai-Hee, Heo, June Seok, Kim, Jun Sung, Jun, Eun Kyoung, Lee, Jung Han, Kim, Aeree, Kim, Jonggun, Whang, Kwang Youn, Kang, Yong-Kook, Yeo, Seungeun, Lim, Hee-Joung, Han, Dong Wook, Kim, Dong-Wook, Oh, Sejong, Yoon, Byung Sun, Schöler, Hans R, You, Seungkwon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193470/
https://ncbi.nlm.nih.gov/pubmed/21709693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.107
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