Transcriptional activation of endoplasmic reticulum chaperone GRP78 by HCMV IE1-72 protein

Glucose-regulated protein 78 (GRP78), a key regulator of endoplasmic reticulum (ER) stress, facilitates cancer cell growth and viral replication. The mechanism leading to grp78 gene activation during viral infection is largely unknown. In this study, we show that the immediate-early 1 (IE1-72) prote...

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Bibliographic Details
Main Authors: Shi-Chen Ou, Derick, Lee, Sung-Bau, Chu, Chi-Shuen, Chang, Liang-Hao, Chung, Bon-chu, Juan, Li-Jung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203653/
https://ncbi.nlm.nih.gov/pubmed/21221131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.10
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