Transcriptional activation of endoplasmic reticulum chaperone GRP78 by HCMV IE1-72 protein

Glucose-regulated protein 78 (GRP78), a key regulator of endoplasmic reticulum (ER) stress, facilitates cancer cell growth and viral replication. The mechanism leading to grp78 gene activation during viral infection is largely unknown. In this study, we show that the immediate-early 1 (IE1-72) prote...

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Библиографические подробности
Главные авторы: Shi-Chen Ou, Derick, Lee, Sung-Bau, Chu, Chi-Shuen, Chang, Liang-Hao, Chung, Bon-chu, Juan, Li-Jung
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2011
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203653/
https://ncbi.nlm.nih.gov/pubmed/21221131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.10
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