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Transcriptional activation of endoplasmic reticulum chaperone GRP78 by HCMV IE1-72 protein
Glucose-regulated protein 78 (GRP78), a key regulator of endoplasmic reticulum (ER) stress, facilitates cancer cell growth and viral replication. The mechanism leading to grp78 gene activation during viral infection is largely unknown. In this study, we show that the immediate-early 1 (IE1-72) prote...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203653/ https://ncbi.nlm.nih.gov/pubmed/21221131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.10 |
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